[Ying-Wen Huang] New Discovery of the Involvement of a Plant Metabolic Enzyme in Bamboo Mosaic Virus Replication
Assistant Professor Ying-Wen Huang and her team identified NbHDR, a key enzyme in the MEP pathway, as an interactor of Bamboo mosaic virus (BaMV) replicase. They further demonstrated that NbHDR promotes the synthesis of positive-strand viral RNA and enhances BaMV replication through a mechanism independent of the gibberellic acid biosynthesis pathway. These findings reveal a new role for a plant metabolic enzyme in viral replication. The study was published in Molecular Plant Pathology (Wong et al., 2025).
Article source: https://bsppjournals.onlinelibrary.wiley.com/doi/full/10.1111/mpp.70099