Academic Research

Professor Cheng-Chung Chang and his team developed a novel surface-enhanced Raman scattering (SERS) substrate by depositing silver nanoparticles on a silver thin film-coated photoresist microcone array. This design significantly enhanced hotspot effects and enabled highly sensitive detection, including Rhodamine 6G at concentrations as low as 10⁻¹² M, as well as reproducible HbA1c detection under simulated real-sample conditions. These findings demonstrate the strong potential of this substrate for sensitive biosensing applications. The study was published in IEEE Sensors Journal (Lin et al., 2024).

Article source: https://ieeexplore.ieee.org/abstract/document/10351037/authors#authors