Academic Research

Academician Shyi-Dong Yeh and his team developed a two-in-one live vaccine by co-inoculating cucurbit plants, including horn melon, muskmelon, and watermelon, with two mild virus strains: either Papaya ringspot virus HA5-1 or PRSV-WAC carrying the R181I and D397N mutations in HC-Pro, together with Zucchini yellow mosaic virus ZYMV-ZAC. They demonstrated that the two mild viruses did not interfere with each other’s accumulation in the host and did not produce synergistic effects on symptom development. This two-in-one vaccine provided concurrent and highly effective protection against the devastating diseases caused by Papaya ringspot virus W type and Zucchini yellow mosaic virus in cucurbits, highlighting its strong potential for practical disease management. The study was published in Phytopathology (Tran et al., 2023).

Article source: https://apsjournals.apsnet.org/doi/full/10.1094/PHYTO-01-23-0019-R