Academic Research

Dr. Choun-Sea Lin and his team established a protoplast-to-plant regeneration system for Salvia miltiorrhiza and applied transgene-free CRISPR/Cas9-mediated genome editing to target transcription factor genes such as MYB28, MYB36, and MYB98. Their results showed that editing these genes could successfully modulate the biosynthesis of bioactive compounds and alter related phenotypes, providing an effective platform for metabolic engineering in medicinal plants. The study was published in Plant Biotechnology Journal (Hsu et al., 2024).

Article source: https://pmc.ncbi.nlm.nih.gov/articles/PMC11123421/