Academic Research

Professor Chang-Wei Hsieh and his team investigated the physicochemical properties of oyster mushroom polysaccharides, including their antioxidant, moisturizing, collagenase-inhibitory, and elastase-inhibitory activities. The results showed that POPs possessed strong DPPH and ABTS radical-scavenging abilities, good water-retention capacity, and inhibitory effects on collagenase and elastase. After UVA irradiation, the levels of ROS, senescent cells, NF-κB activity, and proinflammatory cytokines increased in Hs68 cells. However, POP-80 showed no significant difference from quercetin in reducing ROS accumulation and senescent cells. These findings suggest that POP-80 has promising potential as a key ingredient for skincare and cosmeceutical applications because of its free radical-scavenging, anti-inflammatory, and photoprotective effects. The study was published in International Journal of Biological Macromolecules (Hsiao et al., 2023).

Article source: https://www.sciencedirect.com/science/article/pii/S0141813022031750