[Miin-Huey Lee] Polyketide synthase gene expression in relation to chloromonilicin and melanin production in Monilinia fructicola
Fang-Yi Yu, Chiu-Min Chiu, Yue-Zhi Lee, Shiow-Ju Lee, Chien-Ming Chou, Bang-Jau You, Dai-Keng Hsieh, Maw-Rong Lee, Miin-Huey Lee, and Richard M. Bostock. 2020. Phytopathology.
Antifungal compound was purified and identified by linear ion trap mass spectrometry as the polyketide chloromonilicin from Monilinia fructicola TW5-4. Ten polyketide synthase (PKS) sequences were then cloned. An MfPKS12-silenced mutant accumulated significantly less melanin, had lower resistance to PEG-induced osmotic stress, and displayed reduced virulence on nectarine fruit.
Article source: https://doi.org/10.1094/PDIS-02-20-0412-RE